Thanks to one of our founders,
David J. Anderson, for his analysis below on comparing CMMI and the DOI.

[DOI] We increase return on investment by making continuous flow of
value our focus.
[CMMI] The CMMI is pretty agnostic on this. It's a "so what". It
doesn't break the CMMI nor does the CMMI ask us to do anything
differently.
#1 is compatible!
[DOI] We deliver reliable results by engaging customers in frequent
interactions and shared ownership.
[CMMI] The CMMI actively encourages stakeholder involvement and has
explicit activities for monitoring it.
#2 is compatible!
[DOI] We expect uncertainty and manage for it through iterations,
anticipation, and adaptation.
[CMMI] The CMMI is founded on the principles of W. Edwards Deming,
his Theory of Profound Knowledge, the theory of variation and the
concepts of special and common cause variation. Although some
explicit text talks about "plan the plan, plan the work, work the
plan" and has very "conformance to plan" language in some of the
practice guidance, there is nothing about uncertainty, variation,
adaptive planning, iterations and anticipation that is incompatible
with CMMI. In fact the new MSF for CMMI Process Improvement does
these things explicitly.
#3 is compatible!
[DOI] We unleash creativity and innovation by recognizing that
individuals are the ultimate source of value, and creating an
environment where they can make a difference.
[CMMI] The CMMI is very big on the idea of creating an
organizational environment for success (where success is defined as
achieving continuous improvement - in a quality assurance sense).
There are explicit process areas around training and organizational
environment. There is nothing in the CMMI which is incompatible with
the DOI's embrace of innovation and creativity.
#4 is compatible!
[DOI] We boost performance through group accountability for results
and shared responsibility for team effectiveness.
[CMMI] Though many formal organizations which follow the CMMI use
RACI designations and have individual accountability, the CMMI is
really agnostic to this. What it asks for is that the agreement is
written down in a Team Charter. Again, MSF for CMMI Process
Improvement exhibits the group accountability and shared
responsibility style with its "team of peers" concept. This is
perfectly compatible with CMMI.
#5 is compatible!
[DOI] We improve effectiveness and reliability through situationally
specifc strategies, processes and practices.
[CMMI] The CMMI explictly expects situationally specific practies
and processes and encourages it with explicit activities aimed at
tayloring processes and practices for specific projects.
#6 is compatible!
Asking the question the other way, "Is there anything in the CMMI
which is incompatible with the DOI?" is also an interesting
question. There are 25 process areas in the CMMI. However, my take
on it is "No!" There is nothing at the process area and goal level
which is incompatible with the DOI. The problems arise at the
interpretation of the specific practices. The DOI was born out of
observation that project management practices as taught in so many
places were leading to undesirable behavior and unfavorable results.
The DOI seeks to reset the mindset, the framework (or paradigm), of
how people think about projects so that they adopt the correct
behavior that leads to good results.
It's perfectly possible to be an agile project manager and be
running a CMMI compliant process.
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